PEDIATRIC URINARY TRACT INFECTIONS AND INCREASING EMERGENCE OF ANTIBACTERIAL RESISTANCE
Keywords:
Antibiotic Susceptibility, Children, Urinary Tract Infection, UropathogensAbstract
The aim of the present work was to determine the spectrum and local antibiotic susceptibility patterns (ASP) of pediatric urinary tract pathogens against the commonly used antibacterials during a thirty-three month study period in West Bengal (India). The overall prevalence of UTI was found to be 196/300 (65.3%). The prevalence of UTI in girls were 117/196 (59.6%) and 79/196 (40.3%) in boys. Escherichia coli was responsible for 53.0% of UTIs in our pediatric population, followed by Proteus spp. (16.8%) and Klebsiella sp. (15.3%). E. coli exhibited the highest percentage of resistance against tetracycline (85.6), followed by ampicillin (67.5) and co-trimoxazole (66.2). Klebsiella sp. showed the highest percentage of resistance against tetracycline (80.8), followed by ciprofloxacin (76.0). Nitrofurantoin was highly effective against E. coli, Klebsiella sp., S. aureus.
References
. UTI Guideline Team, Cincinnati Children's Hospital Medical Center. Evidence-based care guideline for medical management of first urinary tract infection in children 12 years of age or less. http:// www.cincinnatichildrens.org/ svc/ alpha/ h/ health-policy/ uti.htm. Accessed October 15, 2010.
. Martinell J, Claesson I, Lidin-Janson G, Jodal U, Urinary infection, reflux and renal scarring in females continuously followed for 13-38 years, Pediatr Nephrol, 9,1995, 131-136.
. Smellie JM, Ransley PG, Normand IC, Prescod N, Edwards D, Development of new renal scars: a collaborative study, BMJ, 290, 1985, 1957-1960.
. Ashkenazi S, EvenTov S, Samra Z, et al, Uropathogens of various childhood populations and their antibiotic susceptibility. Pediatr Infect Dis J, 10, 1991,742–6.
. Gruneberg GN, Antibiotic sensitivities of urinary pathogens: 1971-1982, J Antimicrob Chemothr, 14, 1984,17-23.
. Kirby WM, Bauer AW, Sherris JC, Turck M. 1966,. Antibiotic susceptibility testing by a standardized single disk method, Am. J. Clin. Pathol, 45,1966, 493–496.
. Fritzsche M, Ammann RA, Droz S et al, Changes in antimicrobial resistance of Escherichia coli causing urinary tract infections in hospitalized children, Euro J Clin Microbiol Infect Dis, 24, 2005, 233-235
. Elpis M, Aggelos T, Maria P et al, Antimicrobial susceptibility of pediatric uropathogens in Thrace, Greece, Int Urol Nephrol, 43, 2011, 549-555.
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Copyright (c) 2013 Payel Choudhury, S. N. Chaudhuri, C. Chattopadhyay (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
